1. Metoprolol interactions and warnings
  2. What is metoprolol?
  3. Side furnishings of metoprolol
  4. Working with your healthcare provider

If you lot have whatsoever medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and data fatigued from medical societies and governmental agencies. However, they are non a substitute for professional medical communication, diagnosis, or treatment.

When you start a new medication, the last affair you desire is to accidentally do something that could undermine what that drug is supposed to be helping y'all with. That's particularly true if y'all're trying to care for something every bit severe as center disease.

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Metoprolol (brand names Lopressor and Toprol XL) is a blazon of drug chosen a beta blocker, commonly used to treat congestive heart failure, breast pain, blood force per unit area, and more. In this commodity, we'll give y'all the run-down on what you demand to know about metoprolol interactions.

Metoprolol interactions and warnings

Certain drugs may interfere with the way metoprolol works. Earlier starting metoprolol, tell your healthcare provider near whatever prescription drugs, as well every bit whatever over-the-counter medicines, vitamins, and herbal supplements you are taking. You may need to change the dose or monitor for side effects while you lot're on metoprolol (NIH, 2017).

There are a few different forms of metoprolol (more than on that beneath), simply they all share similar drug interactions. And then, regardless of the class of metoprolol you're taking, be extra careful (and speak with your healthcare provider!) (DailyMed, 2018):

  • Middle and blood pressure medications: reserpine, other beta-blocking agents (like propranolol), propafenone, hydralazine, calcium-aqueduct blockers (like diltiazem)
  • Mental wellness medications: bupropion (brand proper name Wellbutrin; see Important Condom Information), fluoxetine (brand name Prozac; see Important Prophylactic Information), paroxetine, clonidine, thioridazine
  • Other medications: antiretroviral drugs like ritonavir, antihistamine drugs like diphenhydramine (make proper name Benadryl), antimalarial drugs similar quinidine, antifungal drugs like terbinafine (make name Lamisil)

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This listing does non include all potential drug interactions. Seek medical advice for additional drug information if you have any questions or concerns.

Aside from drug interactions, at that place are a few other things to be aware of when taking metoprolol.

At that place isn't a lot of data on how alcohol affects beta-blockers, but the chances are loftier that healthcare providers will tell you to avert or limit alcohol while taking them.

Alcohol is a central nervous organization (CNS) depressant, which ways that information technology slows down brain activity and its control over your vital functions. That's why consuming booze can crusade drowsiness (Abrahao, 2017). Metoprolol'south side effects include dizziness or lightheadedness, so adding the drug to a few drinks could potentially beal these unwanted effects.

The drug label fifty-fifty lists alcohol as a drug interaction for the extended-release form of metoprolol (metoprolol succinate). Alcohol speeds up the action of metoprolol, and the drug is released into your system faster than expected, which can lead to more side effects (DailyMed, 2018).

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There's been limited enquiry on foods to avoid while taking metoprolol, but different another medications, y'all don't demand to avoid grapefruits or greens with this drug.

Considering metoprolol is a beta-blocker, a blazon of drug known to increment potassium levels in the blood, you might want to exist mindful of potassium-rich foods like meat, bananas, and sugariness potatoes. However, metoprolol but increases your risk of elevated potassium by xiii%, compared to 54% for ACE (angiotensin-converting enzyme) inhibitors, another type of heart medication (Chang, 2016).

Mostly speaking, focus on eating a healthy and balanced diet equally advised for anyone living with a heart condition.

Metoprolol is a category C pregnancy drug, which means that at that place aren't adequate studies in humans to determine whether information technology may impairment a fetus (CHEMM, 2021). If y'all're pregnant and have a eye condition, your healthcare provider will discuss your medication options with you.

Metoprolol is also present in small quantities in breast milk. Nursing mothers should seek medical advice regarding the risks and benefits of using metoprolol (DailyMed, 2018).

Metoprolol can cause some people to experience dizzy, so yous should be cautious when driving, riding a bike, operating heavy machinery, or doing anything else that could exist dangerous while dizzy (NIH, 2017).

We've already mentioned that metoprolol is a medication used to treat a variety of heart conditions, just allow'due south dig a piffling deeper into this drug.

Metoprolol (make names Lopressor and Toprol-XL) belongs to a class of medications known as beta-blockers or beta-adrenergic blocking agents. Metoprolol slows down your heart rate, making information technology easier for your middle to circulate claret throughout your trunk. This mechanism makes information technology an effective drug for treating and preventing various heart conditions, including angina (breast pain), center failure, eye attack, atrial fibrillation (irregular heartbeat), and hypertension (high claret force per unit area) (Morris, 2021).

It comes in three forms:

  • An immediate-release tablet (metoprolol tartrate; brand name Lopressor), taken two to four times per day
  • An extended-release tablet (metoprolol succinate; make name Toprol XL), taken one time per day
  • An injectable class (metoprolol tartrate), given in a hospital setting

The dosage will depend on what it's being used to treat.

Metoprolol is a safety and widely prescribed medication, but information technology does come with a adventure of some side effects.

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The most mutual side effects of metoprolol are mild and tend to get abroad after some time. These include (NIH, 2017):

  • Depression
  • Tiredness
  • Diarrhea
  • Wheezing
  • Shortness of jiff
  • Dry mouth
  • Stomach pain
  • Nausea
  • Weight gain
  • Constipation
  • Hives
  • Dizziness or lightheadedness

At that place is a small risk of more severe side furnishings, similar depression blood force per unit area (hypotension), center block, worsening asthma or other lung conditions, boring middle rate (bradycardia), and worsening heart failure. If you feel these, run into your healthcare provider right away.

If you're experiencing side effects that are bothersome enough to make you want to finish the medication, don't practise then all of a sudden. The FDA has issued a blackness box warning that sudden discontinuation of metoprolol tin can lead to breast pain and center attack. Your healthcare provider tin can help you lot create a rubber plan for tapering off of the medication to avoid serious adverse effects (FDA, 2006).

And if you experience signs of an allergic reaction—hives, difficulty breathing, or swelling—seek immediate medical attention from a healthcare professional person.

Earlier starting metoprolol, review your health information with your healthcare provider. Let them know if you have a history of slow centre rate, center failure, blood circulation problems, thyroid affliction, or pheochromocytoma. You should also consult your provider if y'all're considering metoprolol while meaning, planning to get pregnant, or breastfeeding.

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While taking the medication, your healthcare provider may enquire you to regularly check your claret pressure and pulse to make sure metoprolol isn't causing any negative effects on your blood force per unit area.

If you lot skip a dose, take the missed dose equally before long as possible. If this aligns with the next dose, don't double up. But go along with your regular dosing schedule (NIH, 2017).

Finally, as we stated before, y'all should ever consult your healthcare provider before ending a medication—this is particularly important with metoprolol. Abruptly stopping metoprolol tin can cause severe side effects, such as chest pain and an increased risk of heart attacks, then talk over a program for slowly decreasing the dose earlier stopping this medication.

  1. Abrahao, K. P., Salinas, A. G., & Lovinger, D. M. (2017). Alcohol and the brain: neuronal molecular targets, synapses, and circuits. Neuron, 96(6), 1223–1238. doi: 10.1016/j.neuron.2017.ten.032. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566861/
  2. Chang, A. R., Sang, Y., Leddy, J., Yahya, T., Kirchner, H. L., Inker, L. A., et al. (2016). Antihypertensive medications and the prevalence of hyperkalemia in a large wellness organisation. Hypertension (Dallas, Tex. : 1979), 67(half-dozen), 1181–1188. doi: 10.1161/HYPERTENSIONAHA.116.07363. Retrieved from https://world wide web.ncbi.nlm.nih.gov/pmc/articles/PMC4865437/
  3. DailyMed from the U.Due south. National Library of Medicine and the National Institutes of Health (NIH). (2014). Metoprolol tartrate tablet, pic coated. Retrieved on Nov. 22, 2022 from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=011ee828-5c2a-49b9-bf8e-07f5eb5fc635
  4. DailyMed from the U.S. National Library of Medicine and the National Institutes of Health (NIH). (2018). Metoprolol succinate sheathing, extended-release. Retrieved on Nov. 22, 2022 from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=90aa06a3-100f-4466-b950-506303707b01
  5. Morris, J. & Dunham, A. (2021). Metoprolol. [Updated Jul 13, 2021]. In: StatPearls [Internet]. Retrieved from https://world wide web.ncbi.nlm.nih.gov/books/NBK532923/
  6. U.S. Food & Drug Administration (FDA). (2006). LOPRESSOR (metoprolol tartrate) tablet. Retrieved on Nov. 22, 2022 from https://www.accessdata.fda.gov/drugsatfda_docs/characterization/2008/017963s062,018704s021lbl.pdf
  7. U.S. Nutrient & Drug Administration (FDA). (due north.d.). METOPROLOL SUCCINATE EXTENDED-RELEASE TABLETS. Retrieved on Nov. 22, 2022 from https://www.accessdata.fda.gov/drugsatfda_docs/characterization/2006/019962s032lbl.pdf
  8. U.S. Section of Wellness & Human Services (HHS). (2020). FDA Pregnancy Categories. Retrieved on Nov. 22, 2022 from https://chemm.nlm.nih.gov/pregnancycategories.htm
  9. U.Due south. National Library of Medicine (NIH). (2017). Medline Plus – Metoprolol. Retrieved on Nov. 22, 2022 from https://medlineplus.gov/druginfo/meds/a682864.html#side-effects